[eng] Despite their infrequent occurrence, rare events in stochastic processes can lead to the most
catastrophic outcomes. Much interest has recently been focused on the sampling of rare trajectories and the quantification of their statistics in models of stochastic phenomena. This
problem is computationally demanding if conventional sampling methods are used, so specific
rare-trajectory sampling techniques must be developed to deal with it. The renowned WentzelKramers-Brillouin (WKB) method constitutes a tool to characterise most likely paths describing
rare events in the limit of small noise, but is incapable of describing the statistics of rare trajectories in systems with finite stochasticity. A recently proposed backtracking sampling method
that overcomes this limitation consists of working with so-called stochastic bridges, which are
trajectories generated backwards in time that are constrained to have fixed start and end points.
In this project we explore the WKB and backtracking formalisms in order to sample rare
trajectories in three stochastic models. We first focus on the fading of an epidemic in the
SIS model, reproducing existing results in the literature. We next study the extinction of
a population in a model of chemical reactions for which no rare trajectories have previously
been generated, this being a new contribution of our work. Finally, we focus on the escape
of a Brownian particle from a double-well potential, proposing the backtracking method as a
simpler alternative to the techniques used in the literature to generate trajectories of this rare
stochastic phenomenon. The application of the backtracking method to this model is also a
new contribution of the thesis. In all cases we find that at finite noise levels the stochastic
bridges capture fluctuations around the WKB optimal path. In addition, we show that the
WKB formalism in incapable of characterising most likely paths connecting two stable states,
while the backtracking method can be successfully used to sample trajectories that transit from
one attracting state to another.