[eng] Introduction: In December 2019 the first cases of SARS-CoV-2 virus infection were detected, with the months it became pandemic and forced most countries to establish a state of lockdown. The aim of this study is to evaluate the influence of unhealthy lifestyles during lockdown on different cardiometabolic parameters. Methods: A prospective study was performed in 6.236 workers in a Spanish population between March 2019 and March 2021. Different cardiometabolic parameters were determined before and after pandemic lockdown. Results: An increase in all the parameters analyzed in the post-lockdown period compared to the pre-lockdown period was observed. Conclusions. Lockdown has had a negative impact on cardiometabolic parameters in both sexes