Variables that influence the values of 7 scales that determine the risk of nonalcoholic fatty liver disease and liver fibrosis in 219,477 spanish workers

Abstract

[eng] Introduction: Non-alcoholic fatty liver disease (NAFLD) is a very frequent and multifactorial pathology that can lead to liver fibrosis (LF). The aim of the present study was to assess the influence of sociodemographic variables such as age, sex, social class and tobacco consumption on the increased risk of NASFLD and HF. Material and methods: Descriptive and cross-sectional study in 219.477 Spanish workers in which the influence of age, sex, social class and tobacco consumption on the increased risk of presenting NASH and FH determined with 7 different scales was assessed. We also assessed the concordance and correlation between the different scales using Pearson's and Cohen's kappa indices, respectively. Results: All the EHGNA and FH risk scales have increased values as age increases and as one moves down the social scale. These values are also higher in men. Smoking does not seem to show any effect on the risk of NASH and FH. The degree of correlation of the different scales is high. Conclusions: Age, sex and social class all have an influence on the increased risk of NASH and FH, while smoking has no effect.