Regium- Bonds Are Involved in Protein-Gold Binding

Piña, M.L.N.; Frontera, A.; Bauzá, A.

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dc.contributor.author	Piña, M.L.N.
dc.contributor.author	Frontera, A.
dc.contributor.author	Bauzá, A.
dc.date.accessioned	2025-10-10T08:12:35Z
dc.date.available	2025-10-10T08:12:35Z
dc.identifier.citation	Piña, M.L.N., Frontera, A. i Bauzá, A. (2020). Regium- Bonds Are Involved in Protein-Gold Binding. Journal Of Physical Chemistry Letters, 11(19), 8259-8263. https://doi.org/10.1021/acs.jpclett.0c02295	ca
dc.identifier.uri	http://hdl.handle.net/11201/171606
dc.description.abstract	[eng] The regium−π interaction is an attractive noncovalent force between group 11 elements (Cu, Ag, and Au) acting as Lewis acids and aromatic surfaces. Herein, we report for the first time experimental (Protein Data Bank analysis) and theoretical (RI-MP2/def2-TZVP level of theory) evidence of regium−π bonds involving Au(I) and aromatic amino acids (Phe, Tyr, Trp, and His). These findings might be important in the field of drug design and for retrospectively understanding the role of gold in proteins.	en
dc.format	application/pdf	en
dc.format.extent	8259-8263
dc.publisher	ACS	en
dc.relation	info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/CTQ2017-85821-R/[ES]/[Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i ]	es
dc.relation	info:eu-repo/grantAgreement/FEDER/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/CTQ2017-85821-R/[ES]/[Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i ]	es
dc.relation.ispartof	Journal Of Physical Chemistry Letters, 2020, vol. 11, num.19, p. 8259-8263	en
dc.rights	all rights reserved
dc.subject.classification	54 - Química	ca
dc.subject.other	54 - Chemistry. Crystallography. Mineralogy	en
dc.title	Regium- Bonds Are Involved in Protein-Gold Binding	en
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/acceptedVersion
dc.type	Article
dc.date.updated	2025-10-10T08:12:36Z
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.identifier.doi	https://doi.org/10.1021/acs.jpclett.0c02295